MOTORS, MICROTUBULES AND ORGANELLE DYNAMICS

DODDINGLAB@BRISTOL

Link to University of Bristol, School of Biochemistry web pages

IN SITU CRYO-ELECTON TOMOGRAPHY REVEALS FILAMENTOUS ACTIN WITHIN THE MICROTUBULE LUMEN

Read about our new collaborative work with Danielle Paul and Paul Verkade on microtubule lumenal actin published in Journal of Cell Biology

Link to Paul et al. JCB 2020

FRAGMENT-LINKING PEPTIDE DESIGN AT THE KINESIN-CARGO INTERFACE

Read about Jessica's application of a new 'mash-up' peptide design approach to develop a high-affinity kinesin-1 cargo adaptor ligand in Cell Chemical Biology.

A collaboration with the Woolfson Lab at Bristol and Steiner Lab at King's College London

Link to Cross et al. Cell Chemical Biology 2021

JOIN US IN BRISTOL!

If you would like to come to work or study in this beautiful and vibrant city, please get in touch.
We are involved in a number of University of Bristol PhD programmes and current have funds available for scientists from cell biology, biophysics, structural or chemistry backgrounds interested in postdoctoral work in the lab.

Get in Touch

READ ABOUT OUR SMALL-MOLECULE WORK IN PNAS

Thomas Randall shows for the first time how a kinesin-cargo interface can be targeted using a small molecule

Link to journal site

READ ABOUT OUR WORK WITH ROBERTO STEINER ON Y-ACIDIC CARGO ADAPTORS in eLIFE

Stefano Pernigo and Magda Chegkazi show how kinesin-1 selects a novel cargo adaptor motif in an isoform specific manner